Another beautiful day in the Truckee Meadows!
Another beautiful day in the Truckee Meadows!

What are possible side effects of Depo-Provera?
  • Changes in the menstrual period. During the first year periods usually are irregular and often there is frequent bleeding. Periods can also be heavier/longer, and bleeding could last 30 days or more. After 6-12 months most women have fewer periods and many stop having periods altogether.
  • Pregnancy-like symptoms can occur. These include sore breasts, tiredness, nausea, and abdominal discomfort. These usually go away in 3-6 months.
  • Weight changes may occur because it may increase the appetite. Approximately 66% of women gain weight. However approximately 20% lose weight, and another 10% do not gain or lose weight. The typical weight gain is 5.4 pounds the first year and 8 pounds by the end of the second year. Weight gain can be controlled by diet and exercise.
  • Depression. This may become worse in women who have had problems with depression before. If you notice depression, contact a clinician to talk about the possible relation to Depo.
  • Depo-Provera may cause dark patches on the skin of your face. These patches may continue even after you stop getting the shot and may become worse with sun exposure.
  • Some other reactions that have been reported are headaches, dizziness, nervousness, loss of scalp hair, increase in body hair, and either an increase or a decrease in sex drive.